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Navigating Macrophage Polarization

  • Audrianna Alonso

Macrophages are able to polarize from a basal, naïve state to an M1 or M2 phenotype. M1 pro-inflammatory macrophages are characterized by recognizing and eliminating abnormal cells, while M2 anti...

  • Academic (Thesis, Dissertation, Etc.)
  • English
  • Point Loma Nazarene University
  • WHDL

The Role of the Microbiome in Human Health

  • Verushqa Andrade

The human microbiota is a thriving ecosystem that has remained a great mystery, as we have yet to develop a complete understanding of its complex nature and capabilities. Nonetheless, numerous studies...

  • Academic (Thesis, Dissertation, Etc.)
  • English
  • Point Loma Nazarene University
  • WHDL

A Study of Pencil Urchin Population Genetics at Hannibal Bank

  • Lee Hannah

Hannibal Bank is a seamount-like feature known for its high productivity and biodiversity that is located in an UNESCO World Heritage Site off the Pacific coast of Panama. The biodiversity and...

  • Academic (Thesis, Dissertation, Etc.)
  • English
  • Point Loma Nazarene University
  • WHDL

Plasmid-Mediated Transfer of Antibiotic Resistance Genes within Biofilms

  • Madelaine Brown

The objective of this study was to determine transfer frequencies of multidrug resistance plasmids under different conjugation conditions: liquid cultures, batch biofilms, and drip-flow biofilms...

  • Academic (Thesis, Dissertation, Etc.)
  • English
  • Point Loma Nazarene University

Cancer Proliferation Mediated by Tumor-Associated Macrophages (TAMs)

  • Bridget Fortin
  • Allison L. Hale

Macrophages are a type of immune cell present in the tumor micro environment that can be polarized by the cancer cells to aid in the growth and proliferation of the tumor. The goal of this study was...

  • Academic (Thesis, Dissertation, Etc.)
  • English
  • Point Loma Nazarene University

Visualizing the Degradation of pRb by the High-Risk HPV Protein E7

  • Connor A. Lowey
  • Andrew C. Greer

The oncoprotein E7 coded for by the human papillomavirus (HPV) is known to degrade the tumor suppressor retinoblastoma protein (pRb). Transient transfections of a plasmid coding for the E7 protein...

  • Academic (Thesis, Dissertation, Etc.)
  • English
  • Point Loma Nazarene University

Fate of Acrolein, an Agricultural Biocide, Overtime

  • Dakota Brady

Acrolein is an efficient agricultural herbicide within irrigation canal ditches and a biocide within oilfield water-flood systems. The fate of acrolein is typically attributed to evaporation, however...

  • Academic (Thesis, Dissertation, Etc.)
  • English
  • Point Loma Nazarene University

A Study of Genes Expressed in Immunoglobulin M B Cells

  • Christiana Crook

Bony fish are the most primitive vertebrates to possess an adaptive immune system. The zebrafish (Danio rerio) is one example of these bony fish, which means they have an immune system similar to that...

  • Academic (Thesis, Dissertation, Etc.)
  • English
  • Point Loma Nazarene University
  • WHDL

Long Term Consequences of Repeated Brain Injury - A Cadaveric Study

  • Elena Devaney Morris

The purpose of this paper was to examine the long term consequences of repeated brain injury through a cadaveric dissection. For this literature review, the limbic system will be the anatomical...

  • Academic (Thesis, Dissertation, Etc.)
  • English
  • Point Loma Nazarene University